Pitt, Sidney: search on Z-Library

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1

Design, Synthesis, and Anti-inflammatory Properties of Orally Active 4-(Phenylamino)-pyrrolo[2,1- f ][1,2,4]triazine p38α Mitogen-Activated Protein Kinase Inhibitors

Hynes, John, Dyckman, Alaric J., Lin, Shuqun, Wrobleski, Stephen T., Wu, Hong, Gillooly, Kathleen M., Kanner, Steven B., Lonial, Herinder, Loo, Derek, McIntyre, Kim W., Pitt, Sidney, Shen, Ding Ren, S

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 505 KB

english, 2008

2

Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56Lck

John Wityak, Jagabandhu Das, Robert V. Moquin, Zhongqi Shen, James Lin, Ping Chen, Arthur M. Doweyko, Sidney Pitt, Suhong Pang, Ding Ren Shen, Qiong Fang, Henry F. de Fex, Gary L. Schieven, Steven B.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 224 KB

english, 2003

3

Implications of geographical variation on clinical outcomes of cardiovascular trials

Robert J. Mentz, Juan-Carlos Kaski, Gheorghe-Andrei Dan, Sidney Goldstein, Norman Stockbridge, Angeles Alonso-Garcia, Luis M. Ruilope, Felipe A. Martinez, Faiez Zannad, Bertram Pitt, Mona Fiuzat, Chri

Journal:

American Heart Journal

Year:

2012

Language:

english

File:

PDF, 633 KB

english, 2012

4

β-Agonist-induced alterations in organ weights and protein content: Comparison of racemic clenbuterol and its enantiomers

Daniel A. Von Deutsch, Imad K. Abukhalaf, Lawrence E. Wineski, Hassan Y. Aboul-Enein, Sidney A. Pitts, Brian A. Parks, Robert A. Oster, Douglas F. Paulsen, David E. Potter

Journal:

Year:

2000

Language:

english

File:

PDF, 167 KB

english, 2000

5

The discovery of (R)-2-(sec-butylamino)-N-(2-methyl-5-(methylcarbamoyl)phenyl) thiazole-5-carboxamide (BMS-640994)—A potent and efficacious p38α MAP kinase inhibitor

John Hynes Jr., Hong Wu, Sidney Pitt, Ding Ren Shen, Rosemary Zhang, Gary L. Schieven, Kathleen M. Gillooly, David J. Shuster, Tracy L. Taylor, XiaoXia Yang, Kim W. McIntyre, Murray McKinnon, Hongjian

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 212 KB

english, 2008

6

Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56Lck

Ping Chen, Derek Norris, Edwin J. Iwanowicz, Steven H. Spergel, James Lin, Henry H. Gu, Zhongqi Shen, John Wityak, Tai-An Lin, Suhong Pang, Henry F. De Fex, Sidney Pitt, Ding Ren Shen, Arthur M. Dowey

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 138 KB

english, 2002

7

Intracoronary fibrinolytic therapy in acute myocardial infarction: Preliminary report of a randomized trial

Fareed Khaja, Eric Lo, Luis Osterberger, Joseph A. Walton Jr, James F. Brymer, William W. O'Neill, Sidney Goldstein, Bertram Pitt, Tennyson G. Lee, A.David Goldberg

Journal:

The American Journal of Cardiology

Year:

1982

Language:

english

File:

PDF, 157 KB

english, 1982

8

Predictors of total mortality and sudden death in mild to moderate heart failure

Alan Gradman, Prakash Deedwania, Robert Cody, Barry Massie, Milton Packer, Bertram Pitt, Sidney Goldstein

Journal:

Journal of the American College of Cardiology

Year:

1989

Language:

english

File:

PDF, 950 KB

english, 1989

9

Synthesis and SAR of new pyrrolo[2,1-f][1,2,4]triazines as potent p38α MAP kinase inhibitors

Stephen T. Wrobleski, Shuqun Lin, John Hynes Jr., Hong Wu, Sidney Pitt, Ding Ren Shen, Rosemary Zhang, Kathleen M. Gillooly, David J. Shuster, Kim W. McIntyre, Arthur M. Doweyko, Kevin F. Kish, Jeffre

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 251 KB

english, 2008

10

Molecular design, synthesis, and structure–Activity relationships leading to the potent and selective p56lck inhibitor BMS-243117

Jagabandhu Das, James Lin, Robert V. Moquin, Zhongqi Shen, Steven H. Spergel, John Wityak, Arthur M. Doweyko, Henry F. DeFex, Qiong Fang, Suhong Pang, Sidney Pitt, Ding Ren Shen, Gary L. Schieven, Joe

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 228 KB

english, 2003

11

5-Cyanopyrimidine Derivatives as a Novel Class of Potent, Selective, and Orally Active Inhibitors of p38α MAP Kinase

Liu, Chunjian, Wrobleski, Stephen T., Lin, James, Ahmed, Gulzar, Metzger, Axel, Wityak, John, Gillooly, Kathleen M., Shuster, David J., McIntyre, Kim W., Pitt, Sidney, Shen, Ding Ren, Zhang, Rosemary

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 297 KB

english, 2005

12

Pyrazolo-pyrimidines: A novel heterocyclic scaffold for potent and selective p38α inhibitors

Jagabandhu Das, Robert V. Moquin, Sidney Pitt, Rosemary Zhang, Ding Ren Shen, Kim W. McIntyre, Kathleen Gillooly, Arthur M. Doweyko, John S. Sack, Hongjian Zhang, Susan E. Kiefer, Kevin Kish, Murray M

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 274 KB

english, 2008

13

Spontaneous bacterial peritonitis due to Clostridium tertium

Butler, Ted, Pitt, Sidney

Journal:

Gastroenterology

Year:

1982

Language:

english

File:

PDF, 223 KB

english, 1982

14

Benzothiazole based inhibitors of p38α MAP kinase

Chunjian Liu, James Lin, Sidney Pitt, Rosemary F. Zhang, John S. Sack, Susan E. Kiefer, Kevin Kish, Arthur M. Doweyko, Hongjian Zhang, Punit H. Marathe, James Trzaskos, Murray Mckinnon, John H. Dodd,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 202 KB

english, 2008

15

A Small, Automated High-Resolution Analyzer for Determination of Carbohydrates in Body Fluids

Katz, Sidney, Dinsmore, Stanley R, Pitt, W Wilson

Journal:

Clinical Chemistry

Year:

1971

File:

PDF, 675 KB

1971

16

2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent pan-Src Kinase Inhibitor

Das, Jagabandhu, Chen, Ping, Norris, Derek, Padmanabha, Ramesh, Lin, James, Moquin, Robert V., Shen, Zhongqi, Cook, Lynda S., Doweyko, Arthur M., Pitt, Sidney

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 396 KB

english, 2006

17

Role of pH on Sperm-Mucus Interaction

Shulman, Sidney, Pitts, Wesley, Li, Baoyin, Hu, Cheng-yue

Journal:

Fertility and Sterility

Year:

1993

Language:

english

File:

PDF, 479 KB

english, 1993

18

Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis

Spergel, Steven H., Mertzman, Michael E., Kempson, James, Guo, Junqing, Stachura, Sylwia, Haque, Lauren, Lippy, Jonathan S., Zhang, Rosemary F., Galella, Michael, Pitt, Sidney, Shen, Guoxiang, Fura, A

Journal:

ACS Medicinal Chemistry Letters

Year:

2019

File:

PDF, 1.57 MB

2019

19

Modelling heme-mediated brain injury associated with cerebral malaria in human brain cortical organoids

Harbuzariu, Adriana, Pitts, Sidney, Cespedes, Juan Carlos, Harp, Keri Oxendine, Nti, Annette, Shaw, Andrew P., Liu, Mingli, Stiles, Jonathan K.

Journal:

Scientific Reports

Year:

2019

File:

PDF, 3.04 MB

2019

20

Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56lck inhibitors

Jagabandhu Das, Robert V. Moquin, James Lin, Chunjian Liu, Arthur M. Doweyko, Henry F. DeFex, Qiong Fang, Suhong Pang, Sidney Pitt, Ding Ren Shen, Gary L. Schieven, Joel C. Barrish, John Wityak

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 204 KB

english, 2003

21

Discovery of pyrrolo[2,1-f][1,2,4]triazine C6-ketones as potent, orally active p38α MAP kinase inhibitors

Alaric J. Dyckman, Tianle Li, Sidney Pitt, Rosemary Zhang, Ding Ren Shen, Kim W. McIntyre, Kathleen M. Gillooly, David J. Shuster, Arthur M. Doweyko, John S. Sack, Kevin Kish, Susan E. Kiefer, John A.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 948 KB

english, 2011

22

The identification of novel p38α isoform selective kinase inhibitors having an unprecedented p38α binding mode

Wrobleski, Stephen T., Lin, Shuqun, Murali Dhar, T.G., Dyckman, Alaric J., Li, Tianle, Pitt, Sidney, Zhang, Rosemary, Fan, Yi, Doweyko, Arthur M., Tokarski, John S., Kish, Kevin F., Kiefer, Susan E.,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 2.06 MB

english, 2013

23

Utilization of a nitrogen–sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38α MAP kinase inhibitors

Shuqun Lin, Stephen T. Wrobleski, John Hynes Jr., Sidney Pitt, Rosemary Zhang, Yi Fan, Arthur M. Doweyko, Kevin F. Kish, John S. Sack, Mary F. Malley, Susan E. Kiefer, John A. Newitt, Murray McKinnon,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 770 KB

english, 2010

24

The determination of stable organic compounds in waste effluents at microgram per liter levels by automatic high-resolution ion exchange chromatography

Sidney Katz, Wilson W. Pitt Jr., Charles D. Scott, Aaron A. Rosen

Journal:

Year:

1972

Language:

english

File:

PDF, 502 KB

english, 1972

25

Synthesis and SAR of p38α MAP kinase inhibitors based on heterobicyclic scaffolds

T.G. Murali Dhar, Stephen T. Wrobleski, Shuqun Lin, Joseph A. Furch, David S. Nirschl, Yi Fan, Gordon Todderud, Sidney Pitt, Arthur M. Doweyko, John S. Sack, Arvind Mathur, Murray McKinnon, Joel C. Ba

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 307 KB

english, 2007

26

Pathogenesis of the supravalvular aortic stenosis syndrome

Asuquo U. Antia, Hobart E. Wiltse, Richard D. Rowe, Elaine L. Pitt, Sidney Levin, Ole E. Ottesen, Robert E. Cooke

Journal:

The Journal of Pediatrics

Year:

1967

Language:

english

File:

PDF, 1.75 MB

english, 1967

27

Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl- N -propylpyrrolo[1,2- f ][1,2,4]triazine-6-carboxamide (BMS-582949), a Clinical p38α MAP Kinase Inhibitor for the Treatment of Inflammatory Diseases

Liu, Chunjian, Lin, James, Wrobleski, Stephen T., Lin, Shuqun, Hynes, John, Wu, Hong, Dyckman, Alaric J., Li, Tianle, Wityak, John, Gillooly, Kathleen M., Pitt, Sidney, Shen, Ding Ren, Zhang, Rosemary

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.00 MB

english, 2010

28

Neuregulin-1 attenuates mortality associated with experimental cerebral malaria

Solomon, Wesley, Wilson, Nana O, Anderson, Leonard, Pitts, Sidney, Patrickson, John, Liu, Mingli, Ford, Byron D, Stiles, Jonathan K

Journal:

Journal of Neuroinflammation

Year:

2014

Language:

english

File:

PDF, 423 KB

english, 2014

29

Globalization of cardiovascular clinical research: The balance between meeting medical needs and maintaining scientific standards

Wendy Gattis Stough, Faiez Zannad, Bertram Pitt, Sidney Goldstein

Journal:

American Heart Journal

Year:

2007

Language:

english

File:

PDF, 103 KB

english, 2007

30

Muscle-Specific Effects of Hindlimb Suspension and Clenbuterol in Mature Male Rats

Wineski, Lawrence E., von Deutsch, Daniel A., Abukhalaf, Imad K., Pitts, Sidney A., Potter, David E., Paulsen, Douglas F.

Journal:

Cells Tissues Organs

Year:

2002

Language:

english

File:

PDF, 147 KB

english, 2002

31

DNA-Dependent ATPase from HeLa Cells Is Related to Human Ku Autoantigen

Cao, Qiu Ping, Pitt, Sidney, Leszyk, John, Baril, Earl F.

Journal:

Year:

1994

Language:

english

File:

PDF, 2.99 MB

english, 1994

32

Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56Lck inhibitors

Ping Chen, Derek Norris, Jagabandhu Das, Steven H. Spergel, John Wityak, Leslie Leith, Rulin Zhao, Bang-Chi Chen, Sidney Pitt, Suhong Pang, Ding Ren Shen, Rosemary Zhang, Henry F. De Fex, Arthur M. Do

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 352 KB

english, 2004

33

5-Amino-pyrazoles as potent and selective p38α inhibitors

Jagabandhu Das, Robert V. Moquin, Alaric J. Dyckman, Tianle Li, Sidney Pitt, Rosemary Zhang, Ding Ren Shen, Kim W. McIntyre, Kathleen Gillooly, Arthur M. Doweyko, John A. Newitt, John S. Sack, Hongjia

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.29 MB

english, 2010

34

The captopril-digoxin multicenter resarch group study on the comparative steps of captopril and digoxin in patients with mildmoderate heart failure: Implications for therapy

Bertram Pitt, Sidney Goldstein

Journal:

Cardiovascular Drugs and Therapy

Year:

1989

Language:

english

File:

PDF, 270 KB

english, 1989

35

Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis

Spergel, Steven H., Mertzman, Michael E., Kempson, James, Guo, Junqing, Stachura, Sylwia, Haque, Lauren, Lippy, Jonathan S., Zhang, Rosemary F., Galella, Michael, Pitt, Sidney, Shen, Guoxiang, Fura, A

Journal:

ACS Medicinal Chemistry Letters

Year:

2019

Language:

english

File:

PDF, 1.57 MB

english, 2019

36

Chlamydial infection in vitamin D receptor knockout mice is more intense and prolonged than in wild-type mice

He, Qing, Ananaba, Godwin A., Patrickson, John, Pitts, Sidney, Yi, Yeming, Yan, Fengxia, Eko, Francis O., Lyn, Deborah, Black, Carolyn M., Igietseme, Joseph U., Thierry-Palmer, Myrtle

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

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